Mickey's main method of attack is to perform a 'bounce' whilst jumping, which can be used to defeat enemies or to bounce upwards towards higher areas. Mickey can collect projectiles such as apples and marbles to throw at his opponents. There are various items that earn bonus points, increase the player's health and grant extra tries.
Every level ends in a boss battle against each Master of Illusion (Mizrabel's henchmen) where Mickey can earn a gem, although the final two levels award a gem halfway through. After clearing all five levels, obtaining all gems will open up the route to the witch's tower. There, the player faces the final boss: a giant and youthful version of Mizrabel. There is an easy mode available where players play through truncated versions of the first three levels, with no boss fights.
The Master System and Game Gear versions of the game have different game mechanics, enemies, items, levels, and graphics.